2,6-Pyridinedicarbonyl chloride, Pyridine-2,6-dicarboxylic acid chloride

Name	2,6-Pyridinedicarboxylic acid chloride
Synonyms	2,6-Pyridinedicarbonyl chloride 2,6-Bis(chlorocarbonyl)pyridine PYRIDINE-2,6-DICARBONYL CHLORIDE 2,6-Pyridinedicarbonyl dichloride 2,6-PYRIDINEDICARBONYL DICHLORIDE (S)-(-)-1-(4-METHOXYPHENYL)ETHANOL pyridine-2,6-dicarbonyl dichloride 2,6-PYRIDINEDICARBOXYLIC ACID CHLORIDE 2,6-Pyridinedicarboxylic acid chloride PYRIDINE-2,6-DICARBOXYLIC ACID CHLORIDE 2,6-Pyridinedicarbonyl chloride, Pyridine-2,6-dicarboxylic acid chloride
CAS	3739-94-4
EINECS	223-125-4
InChI	InChI=1/C7H3Cl2NO2/c8-6(11)4-2-1-3-5(10-4)7(9)12/h1-3H

Molecular Formula	C7H3Cl2NO2
Molar Mass	204.01
Density	1.4521 (rough estimate)
Melting Point	56-58 °C (lit.)
Boling Point	284 °C (lit.)
Flash Point	284°C
Water Solubility	Insoluble in water.
Vapor Presure	0.00292mmHg at 25°C
Appearance	Crystalline Powder, Crystals or Chunks
Color	White to brown
BRN	131556
pKa	-2.12±0.10(Predicted)
Storage Condition	2-8℃
Sensitive	Moisture Sensitive
Refractive Index	1.6100 (estimate)
MDL	MFCD00006289
Use	2,6-Pyridinedicarbonyl chloride was used as the reagent during the synthesis of pyridine-based polyamido-polyester optically active macrocycles. It was used as starting reagent during the synthesis of pyridine-bridged 2,6-bis-carboxamide Schiff′s bas

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes.
UN IDs	UN 3261 8/PG 2
WGK Germany	3
FLUKA BRAND F CODES	10-19-21
HS Code	29333990
Hazard Class	8
Packing Group	II

NIST chemical information	Information provided by: webbook.nist.gov (external link)
Application	2, 6-pyridine dicarbonyl chloride is an organic intermediate and pharmaceutical intermediate that can be used in acylation reactions. It is mainly used in laboratory research and development. In the process of chemical and pharmaceutical research and development, it can be prepared from 2, 6-pyridinedicarboxylic acid and oxalyl chloride.
preparation	report 1. dissolving 2,6-pyridinedicarboxylic acid (5.00g,30mmol) as raw material in dichloromethane, adding oxalyl chloride (11.43g,90mmol) dropwise at 0 ℃, heating the solution to 25 ℃ after the dropwise addition, stirring the reaction to produce 2,6-pyridinedicarboxylic chloride in a yield of 95%; it is reported that the 2. dissolves 2, 6-pyridinedicarboxylic acid in dichloromethane, then adds a certain amount of dichlorosulfoxide, and refluxes at 70°C to remove the pyridine -2, 6-dicarboxylic acid Two carboxyl acyl chlorides are chlorinated, and finally the impurities produced are removed to prepare 2, 6-pyridine dicarbonyl chloride.

Last Update：2024-04-09 21:11:58

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Product Name: Ethyl (S)-(-)-4-chloro-3-hydroxybutyrate Request for quotation
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2,6-Pyridinedicarbonyl chloride, Pyridine-2,6-dicarboxylic acid chloride Request for Quotation